Fasting Insulin

Medical information:

  • A single random blood sample for insulin may provide insufficient information due to wide variation in the time responses of insulin levels and blood glucose.
  • Stimulation of insulin secretion may be caused by many factors like hyperglycemia, glucagon, amino acids, growth hormone and catecholamines.
  • Interference in insulin assay is seen due to insulin antibodies which develop in patients treated with bovine or porcine insulin.

Clinical utility :

  • Evaluation of fasting hypoglycemia
  • Evaluation of polycystic ovary syndrome
  • Classification of Diabetes mellitus
  • Assessment of Beta cell activity
  • Select optimal therapy for Diabetes
  • Investigation of insulin resistance

Increased levels :

  • Insulinoma
  • Type II diabetic patients
  • Infantile hypoglycemia
  • Hyperinsulinism
  • Obesity
  • Cushing’s syndrome
  • Oral contraceptives
  • Hyperthyroidism

Decreased levels :

  • Untreated type I Diabetes Mellitus